Description
What is MOTS-C?
MOTS-C is a unique, naturally occurring 16-amino-acid peptide encoded by the mitochondrial genome rather than nuclear DNA. It represents a class of signalling agents that communicate with the cell nucleus to help regulate adaptive metabolic responses.
MOTS-C 10mg is supplied exclusively for laboratory and scientific research purposes. It is intended for controlled analytical environments where compound identity, handling, and storage consistency are required. Each vial contains 10mg of MOTS-C as a lyophilised white powder, verified through mass spectrometry and tested for purity to support consistency and reliability in research procedures.
Frequently Studied Properties
Researchers use this peptide in genetic and cellular models to investigate its role in metabolic homeostasis, specifically focusing on:
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Interaction with the AMPK (AMP-activated protein kinase) pathway, a critical cellular energy sensor
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Regulation of glucose uptake and fatty acid oxidation at a non-nuclear and systemic level
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The structural mechanism by which MOTS-C translocates to the cell nucleus under different metabolic stress conditions
Simple Storage & Lab Protocols
Storage of these compounds is important — follow these protocols to keep them stable:
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Keep the peptide dry and sealed in a freezer at −20°C for long-term stability.
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For short-term storage, keep it in a laboratory refrigerator at approximately 4°C, completely away from direct light.
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Once reconstituted with a suitable laboratory liquid, store it exclusively in the fridge and use it within 20 days.
Never freeze the solution once mixed, as this affects structural integrity.
Key Features
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Mitochondria-derived 16-amino-acid peptide
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≥99% purity — HPLC tested, COA provided
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10mg research vial — lyophilised powder
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Fast UK dispatch
Specifications
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Amino Acid Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR)
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Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
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Molecular Weight: 2,174.64 g/mol
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Amino Acids: 16
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Quantity: 10mg per vial
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Purity: ≥99% (HPLC)
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Form: Lyophilised powder
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Storage: −20°C long-term; 4°C post-reconstitution
For research use only. Not intended for human consumption.




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